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Michelle Michels Selected Research

Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)

10/2022Blood-based biomarkers for the prediction of hypertrophic cardiomyopathy prognosis: a systematic review and meta-analysis.
1/2022Contemporary family screening in hypertrophic cardiomyopathy: the role of cardiovascular magnetic resonance.
12/2021Effect of Mavacamten on Echocardiographic Features in Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.
10/2021Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy.
1/2021Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.
1/2021Usefulness of High-Sensitivity Cardiac Troponin T to Predict Long-Term Outcome in Patients with Hypertrophic Cardiomyopathy.
1/2021Novel Morphological Features on CMR for the Prediction of Pathogenic Sarcomere Gene Variants in Subjects Without Hypertrophic Cardiomyopathy.
1/2021Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation.
1/2021Sex-Related Differences in Protein Expression in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy.
10/2020Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.
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Michelle Michels Research Topics

Disease

36Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
10/2022 - 11/2007
11Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2021 - 05/2010
8Cardiomyopathies (Cardiomyopathy)
10/2021 - 11/2007
6Heart Failure
10/2022 - 01/2015
4Stroke (Strokes)
10/2022 - 01/2016
4Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2022 - 01/2009
4Atrial Fibrillation
10/2020 - 10/2008
3Cardiac Arrhythmias (Arrythmia)
10/2022 - 01/2015
3Familial Hypertrophic Cardiomyopathy (Cardiomyopathy, Familial Hypertrophic)
10/2020 - 03/2009
3Cardiomegaly (Heart Hypertrophy)
01/2020 - 12/2013
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2019 - 11/2007
2Left Ventricular Outflow Obstruction
12/2021 - 01/2021
2Fibrosis (Cirrhosis)
01/2020 - 01/2018
2Heart Arrest (Cardiac Arrest)
01/2020 - 10/2018
2Aortic Valve Stenosis (Aortic Stenosis)
06/2019 - 05/2017
2Disease Progression
01/2018 - 04/2015
2Ventricular Tachycardia
01/2018 - 05/2010
2Heart Diseases (Heart Disease)
12/2015 - 01/2015
1Sudden Death
10/2020
1Chest Pain (Chest Pains)
01/2020
1Shock
01/2020
1Conversion Disorder (Astasia Abasia)
01/2018
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2017
1Myocardial Infarction
02/2016
1Glycogen Storage Disease Type II (Pompe's Disease)
02/2016
1Inborn Genetic Diseases (Disease, Hereditary)
01/2016
1Cardiovascular Diseases (Cardiovascular Disease)
05/2011
1Ventricular Fibrillation
05/2010
1Death (Near-Death Experience)
05/2010

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
01/2021 - 03/2009
6Cardiac MyosinsIBA
12/2021 - 01/2009
5DNA (Deoxyribonucleic Acid)IBA
01/2022 - 06/2010
4Troponin T (Troponin T1)IBA
10/2022 - 02/2016
4myosin-binding protein CIBA
10/2020 - 01/2009
4Carrier Proteins (Binding Protein)IBA
01/2015 - 01/2009
3Biomarkers (Surrogate Marker)IBA
10/2022 - 04/2015
3TroponinIBA
01/2021 - 01/2018
3Myosins (Myosin)IBA
10/2020 - 12/2015
3ConnectinIBA
01/2020 - 01/2018
3GadoliniumIBA
01/2018 - 01/2017
2Brain Natriuretic Peptide (Natrecor)FDA Link
10/2022 - 12/2021
2Acetates (Acetic Acid Esters)FDA Link
01/2020 - 05/2017
2Messenger RNA (mRNA)IBA
02/2016 - 12/2013
2Troponin IIBA
02/2016 - 12/2013
1LDL CholesterolIBA
10/2022
1C-Reactive ProteinIBA
10/2022
1MYK-461IBA
12/2021
1sulconazole (Myk)FDA Link
12/2021
1TubulinIBA
01/2021
1trans-crotonin (CTN)IBA
01/2021
1Protein Isoforms (Isoforms)IBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2019
1Oxygen (Dioxygen)IBA
05/2017
1Antihypertensive Agents (Antihypertensives)IBA
04/2016
1Transcription Factors (Transcription Factor)IBA
02/2016
1Phosphotransferases (Kinase)IBA
02/2016
1Creatine Kinase (Creatine Phosphokinase)IBA
02/2016
1Adenosine Diphosphate (ADP)IBA
12/2015
1pro-brain natriuretic peptide (1-76)IBA
01/2015
14-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
01/2015
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
08/2014
1MicroRNAs (MicroRNA)IBA
12/2013
1beta Adrenergic ReceptorsIBA
12/2013
1Mutant Proteins (Protein, Mutant)IBA
01/2012
1Pharmaceutical PreparationsIBA
10/2008
1Ventricular MyosinsIBA
11/2007

Therapy/Procedure

12Therapeutics
01/2020 - 05/2012
10Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
10/2021 - 05/2012
2Heart Transplantation (Grafting, Heart)
01/2021 - 10/2018
1Heart-Assist Devices
10/2020
1Length of Stay
01/2018
1Defibrillators (Defibrillator)
05/2010